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KMID : 0614619920240010123
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Korean Journal of Gastroenterology
1992 Volume.24 No. 1 p.123 ~ p.131
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Carcinoma of Gastric and Colon in Association with Familial Adenomatous Polyposis
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함기백
홍성란/방수관/최규식/안용진/백승운/김은주/윤세옥/유승익
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Abstract
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Familial adenomatous polyposis (FAP) includes early development of up to thousands of colorectal adenoma and of colonic adenocarcinoma in all untreated cases. Moreover a variety of extracolouic manifestation are seen. Several reports have
demonstrated a
high incidence of gastroduodenal polyps in FAP patient. Fundic gland polypois is found in half of polyposis patient. It is an non-geoplastic condition with hundreds of sessile polyps in the gastric fundus consisting of cystic dilated fundic
glands
without epithelial dysplasia. In western countries, gastric adenoma and carcinoma are rare findings in FAP patients. Until present time, only 2 cases in western countries and 8 cases in Japanese series were reported in literature. So it is
generally
suggested that the development of gastric carcinoma is related not only to racial and environmental factors, but also to a genetic effect, this may by the first case report in Korea.
Here we report the case with familial adenomatous polyposis, presenting with gastric and colonic adenocarcinoma.
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KEYWORD
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